nucleases - ορισμός. Τι είναι το nucleases
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Τι (ποιος) είναι nucleases - ορισμός

CLASS OF ENZYMES
Nucleases; Polynucleotidase; Nucleodepolymerase; Site specific nuclease
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Nuclease         
A nuclease (also archaically known as nucleodepolymerase or polynucleotidase) is an enzyme capable of cleaving the phosphodiester bonds between nucleotides of nucleic acids. Nucleases variously effect single and double stranded breaks in their target molecules.
nuclease         
['nju:kl?e?z]
¦ noun Biochemistry an enzyme that cleaves nucleic acid chains into smaller units.
Zinc finger nuclease         
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CLASS OF ARTIFICIAL ENZYMES
Zinc finger nucleases; Zinc finger protein nucleases; Zinc-finger nuclease; Nucleasas con dedos de zinc; ZFNs
Zinc-finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA-binding domain to a DNA-cleavage domain. Zinc finger domains can be engineered to target specific desired DNA sequences and this enables zinc-finger nucleases to target unique sequences within complex genomes.

Βικιπαίδεια

Nuclease

A nuclease (also archaically known as nucleodepolymerase or polynucleotidase) is an enzyme capable of cleaving the phosphodiester bonds between nucleotides of nucleic acids. Nucleases variously effect single and double stranded breaks in their target molecules. In living organisms, they are essential machinery for many aspects of DNA repair. Defects in certain nucleases can cause genetic instability or immunodeficiency. Nucleases are also extensively used in molecular cloning.

There are two primary classifications based on the locus of activity. Exonucleases digest nucleic acids from the ends. Endonucleases act on regions in the middle of target molecules. They are further subcategorized as deoxyribonucleases and ribonucleases. The former acts on DNA, the latter on RNA.